浩瀚色譜（山東）應用技術開發有限公司通過玻璃球填充柱氣相色譜法測定藥典二氧化碳中碳氫化合物的含量，是一個成熟、專屬性強的方法。其核心在于使用惰性的玻璃球填料色譜柱分離、FID檢測器檢測，并通過外標法定量，最終判斷產品中碳氫化合物雜質是否低于0.0020%的限度。
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所需材料與設備
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氣相色譜儀系統：需配備氫火焰離子化檢測器（FID）?和相應的氣體進樣閥或手動進樣系統1。
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玻璃球色譜柱：這是核心組件。推薦使用0.8m長度 × 4mm內徑，內填80目玻璃球的色譜柱（浩瀚色譜的HH-BLQ型號）。這種柱子是惰性的，對二氧化碳基質中的低碳數烴類（如甲烷）有良好的分離能力。
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高純載氣與檢測器氣體：通常使用高純氮氣或氦氣作為載氣。氫氣和空氣（或壓縮空氣）作為FID的燃燒氣和助燃氣。務必確保氣體純度，載氣中的氧氣含量最好不超過1 ppm，以免高溫下損壞色譜柱固定相或影響基線。
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標準氣體：甲烷標準氣，其中甲烷在氮氣中的濃度為0.0020%（體積分數），用于外標法定量36。
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待測二氧化碳樣品：藥典規定的二氧化碳樣品
名稱：玻璃球色譜柱
規格：0.8m*4mm，80目
zui高使用溫度：300°C
應用：藥典二氧化碳2020年版：碳氫化合物的測定
浩瀚色譜（山東）應用技術開發有限公司，研制生產的玻璃球色譜柱安裝在島津，安捷倫，賽默飛，瓦里安，布魯克，PE等儀器上，柱效高，分離好，峰型對稱，滿足藥典的指標要求。
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適用于：
安捷倫490在線/便攜，4890,5890,6890,7820,7890,8860,8890
島津GC-14C，GC-2010，GC-2014，GC-2030
賽默飛1310,1300,1610,1600
瓦里安3800系列
布魯克PE580,590,680,690
磐諾A90，福立GC9790，華愛，天瑞，天美，GC7900，川儀，北分瑞利，東西電子，魯南瑞虹，捷島/科曉
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Haohan Chromatography (Shandong) Application Technology Development Co., Ltd. uses glass ball packed column gas chromatography to determine the content of hydrocarbons in pharmacopoeia carbon dioxide, which is a mature and highly specific method. The core lies in the use of inert glass ball packing chromatography columns for separation, FID detector detection, and quantification through external standard method to ultimately determine whether the hydrocarbon impurities in the product are below the limit of 0.0020%.
Required materials and equipment
Gas chromatograph system: A hydrogen flame ionization detector (FID) and corresponding gas injection valve or manual injection system 1 are required.
Glass sphere chromatography column: This is the core component. Recommend using a chromatography column with a length of 0.8m and an inner diameter of 4mm, filled with 80 mesh glass spheres (HH-BLQ model of Haohan Chromatography). This type of column is inert and has good separation ability for low-carbon hydrocarbons (such as methane) in the carbon dioxide matrix.
High purity carrier gas and detector gas: High purity nitrogen or helium gas is usually used as the carrier gas. Hydrogen and air (or compressed air) are used as combustion gases and auxiliary gases for FID. It is necessary to ensure the purity of the gas, and the oxygen content in the carrier gas should preferably not exceed 1 ppm to avoid damaging the chromatographic column stationary phase or affecting the baseline at high temperatures.
Standard gas: Methane standard gas, with a concentration of 0.0020% (volume fraction) of methane in nitrogen, used for external standard method quantification of 36.
Carbon dioxide sample to be tested: the carbon dioxide sample specified in the pharmacopoeia
Name: Glass Ball Chromatography Column
Specification: 0.8m * 4mm, 80 mesh
Maximum operating temperature: 300 ° C
Application: Pharmacopoeia Carbon Dioxide 2020 Edition: Determination of Hydrocarbons
Haohan Chromatography (Shandong) Application Technology Development Co., Ltd. has developed and produced glass sphere chromatography columns that are installed on instruments such as Shimadzu, Agilent, Thermo Fisher Scientific, Varian, Bruker, PE, etc. The columns have high column efficiency, good separation, symmetrical peak shapes, and meet the requirements of pharmacopoeia.
Suitable for:
Agilent 490 online/portable, 48905890689088608890
Shimadzu GC-14C, GC-2010, GC-2014, GC-2030
Thermo Fisher Scientific 1310130016101600
Varian 3800 Series
Brooke PE580590680690
Panno A90, Fuli GC9790, Huaai, Tianrui, Tianmei, GC7900， Chuanyi, Beifen Ruili, Dongxi Electronics, Lunan Ruihong, Jiedao/Kexiao
滕州市浩瀚色譜儀器技術服務有限公司
電話：0632-5667636
傳真：0632-5667636
手機：15562228838,13963221227
地址：山東滕州市平行路（商務部和技術部）
郵箱：[email protected]
QQ:1404939462
聯系人：王經理
網址：www.shoxu.cn